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Smurf1-IN-A01, MedChemExpress

Product Code. 16490687
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Product Code. 16490687 Supplier Medchem Express Supplier No. HY110195

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Description

MedChemExpress Smurf1-IN-A01 (A01) is an ubiquitin ligase Smad ubiquitination regulatory factor-1 (Smurf1) inhibitor with a kd of 3.664 nM, which increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.

Smurf1-IN-A01 (A01) is an ubiquitin ligase Smad ubiquitination regulatory factor-1 (Smurf1) inhibitor with a kd of 3.664 nM, which increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.

Specifications

Chemical Name or Material Smurf1-IN-A01
CAS 1007647-73-5
Color Off-White
Purity Grade Notes Research
Molecular Formula C22H20ClF3N4O3S
Quantity 50 mg
Synonym A01
Solubility Information DMSO : 62.5 mg/mL (121.85 mM; Need ultrasonic)
SMILES O=S(C1=CC(C(F)(F)F)=C(Cl)C=C1)(N2CCN(C(C3=CC=C(N4C(C)=CC=N4)C=C3)=O)CC2)=O
Molecular Weight (g/mol) 512.93
Formula Weight 512.93
Percent Purity 99.58%
Grade Research
Physical Form Solid
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