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SPP-86, MedChemExpress

Product Code. 16497077
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Quantity:
5 mg
Unit Size:
5mg
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Product Code. 16497077

Brand: Medchem Express HY110193

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This item is not returnable. View return policy

Description

MedChemExpress SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC50 of 8 nM. SPP-86 inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling, also inhibits RET-induced estrogen receptorα (ERα) phosphorylation in MCF7 cells.

SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC50 of 8 nM. SPP-86 inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling, also inhibits RET-induced estrogen receptorα (ERα) phosphorylation in MCF7 cells.

Specifications

Chemical Name or Material SPP-86
Physical Form Solid
CAS 1357349-91-7
Color Light Nude
Quantity 5 mg
Purity Grade Notes Research
Molecular Formula C16H15N5
For Use With (Application) Neuroscience-Neuromodulation
Solubility Information DMSO : 100 mg/mL (360.59 mM; Need ultrasonic)
SMILES CC(C)N1C2=NC=NC(N)=C2C(C#CC3=CC=CC=C3)=N1
Molecular Weight (g/mol) 277.32
Formula Weight 277.32
Percent Purity 98.04%
Grade Research
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Research purposes only

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