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  6. Thermo Scientific™ SurePac™ Protein RP MDi™ HPLC Columns

Thermo Scientific™ SurePac™ Protein RP MDi™ HPLC Columns

Product Code. 31902952 Shop All Thermo Scientific Products
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Diameter (Metric):
2.1 mm
300 μm
Length (Metric):
20 mm
50 mm
100 mm
Unit Size:
Each
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Product Code. Diameter (Metric) Length (Metric) Unit Size
31902952 2.1 mm 50 mm Each
31902951 2.1 mm 20 mm Each
31902954 2.1 mm 100 mm Each
31902953 300 μm 50 mm Each
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Product Code. 31902952 Supplier Thermo Scientific™ Supplier No. 43722052132
 Restricted Item
Estimated Shipment: 02-11-2026
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Description

SurePac Protein RP MDi is a bioinert reversed-phase column engineered for robust HPLC and LC-MS analysis of intact proteins, mAbs and ADCs. It minimizes unspecific interactions with the column hardware, improves recovery, and delivers reproducible, high-resolution separations for sensitive therapeutic proteins workflows.

Thermo Scientific™ SurePac™ Protein RP MDi™ HPLC columns deliver high-resolution, reproducible separations for monoclonal antibodies, antibody subunits, and ADCs across development and QC workflows. Built on monodisperse, supermacroporous polymeric particle technology with bio-inert hardware, they provide stable performance under elevated temperatures used in LC-MS, enabling consistent peak shape, reliable resolution, and durable operation for scalable protein analysis.

  • Designed for reversed-phase protein separations
  • Engineered for intact proteins, mAbs and ADCs, delivering reliable retention and selectivity across a wide range of molecular weights.
  • Bioinert, metal-free flow path
  • Optimized for LC-MS protein workflows
  • Fully compatible with MS-friendly mobile phases, enabling sensitive and reproducible detection of intact proteins and peptide maps.
  • Robust stationary phase for high-temperature operation
  • Maintains stable performance under elevated temperatures and high organic conditions, supporting fast gradients and durable methods.
  • Excellent peak shape and resolution
  • Delivers sharp, symmetrical peaks and effective separation of protein variants, isoforms, and closely related species.
  • Reproducible performance across columns and batches
  • Tight manufacturing controls ensure consistent results and smooth method transfer between instruments and laboratories.
  • Suitable for development and routine analysis
  • Supports method development, characterization, and QC workflows, reducing the need for multiple column chemistries.
  • Compatible with UHPLC and HPLC systems
TRUSTED_SUSTAINABILITY

Specifications

Column Format Analytical
Diameter (Metric) 2.1 mm
Flow Rate 0.2 to 0.6 mL/min.
Length (Metric) 50 mm
Max. Pressure 6500 psi (448 bar)
Particle Size 2.5 μm
pH 2 to 12
Pore Size Proprietary supermacroporous
Temperature 5°C to 90°C
Stationary Phase Poly-DVB
Packing Material Polymeric
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