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T Cell Receptor Gamma/Delta Hamster, anti-Mouse, Biotin, Clone: GL3, STEMCELL Technologies
Hamster Monoclonal Antibody
172.80 € - 642.60 €
Specifications
| Antigen | T Cell Receptor Gamma/Delta |
|---|---|
| Clone | GL3 |
| Applications | Immunohistochemistry, Flow Cytometry, Immunofluorescence, Functional Assay, Blocking Assay |
| Classification | Monoclonal |
| Conjugate | Biotin |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17119031
|
Stemcell Technologies
60104BT.2 |
50 μg |
172.80 €
50µg |
Estimated Shipment: 04-06-2024 Log in to see stock. |
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|
17109031
|
Stemcell Technologies
60104BT.1 |
100 μg |
338.85 €
100µg |
Estimated Shipment: 16-05-2024 Log in to see stock. |
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|
17199021
|
Stemcell Technologies
60104BT |
500 μg |
642.60 €
500µg |
Estimated Shipment: 04-06-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
- The GL3 antibody reacts with the δ chain of the murine T cell receptor γ/δ (TCRγ/δ or TCR gamma/delta), a subtype of the TCR involved in the recognition of both peptide and lipid antigens
- TCRγ/δ comprises a heterodimer (∼ 80 kDa in humans) of disulfide-linked γ and δ subunits that associates with CD3 on the cell surface
- It is a member of the immunoglobulin superfamily
- TCRγ/δ is expressed on a subpopulation of T cells in the circulation but may be found on up to 50% of the T cells in epithelial cell-rich tissues
- These cells have roles in oral and tumor-associated tolerance as well as autoimmune disease and have been described as a link between the adaptive and innate immune responses
- Once activated, they secrete effector cytokines in a subtype- and context-specific manner
- Most γ/δ T cells are CD4-/CD8-, though some express CD8
- The GL3 antibody recognizes an epitope in the constant region of the δ chain and can reportedly activate TCRγ/δ+ cells
Specifications
| T Cell Receptor Gamma/Delta | |
| Immunohistochemistry, Flow Cytometry, Immunofluorescence, Functional Assay, Blocking Assay | |
| Biotin | |
| Mouse | |
| Primary |
| GL3 | |
| Monoclonal | |
| Hamster | |
| IgG2 κ |