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Invitrogen™ TACC3 Recombinant Rabbit Monoclonal Antibody (24GB1940)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA557757

 View more versions of this product

Product Code. 30276673

  • 198.00 € / 20µL

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Description

Description

TACC3 Recombinant Monoclonal Antibody for Western Blot, Flow

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TACC3
Recombinant Monoclonal
Unconjugated
TACC3
Aint; Arnt interacting protein; ARNT-interacting protein; C86661; ERIC1; ERIC-1; Tacc3; transforming acidic coiled coil 3; transforming acidic coiled-coil containing protein 3; transforming acidic coiled-coil-containing protein 3; transforming, acidic coiled-coil containing protein 3
Rabbit
Affinity chromatography
RUO
10460, 360962
-20°C
Liquid
Flow Cytometry, Western Blot, Immunocytochemistry
24GB1940
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q9Y6A5
TACC3
A synthesized peptide derived from human TACC3 (aa 50-100).
20 μL
Primary
Human, Rat
Antibody
IgG
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