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Tamoxifen, MedChemExpress

Product Code. p-200096829
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Quantity:
500 mg
1 g
5 g
Unit Size:
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500mg
5g
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Product Code. Quantity unitSize
16491379 1 g 1g
16431706 500 mg 500mg
16488497 5 g 5g
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Product Code. 16491379 Supplier Medchem Express Supplier No. HY13757A

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Description

MedChemExpress Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells.

Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 μM and 1.8 μM, respectively. Tamoxifen activates autophagy and induces apoptosis. Tamoxifen also can induce gene knockout of CreER(T2) transgenic mouse.

Specifications

Chemical Name or Material Tamoxifen
CAS 10540-29-1
Color White
Purity Grade Notes Research
Molecular Formula C26H29NO
Quantity 1 g
Synonym ICI 47699 (Z)-Tamoxifen trans-Tamoxifen
Solubility Information DMSO : 50 mg/mL (134.59 mM; Need ultrasonic) ∣Ethanol : 50 mg/mL (134.59 mM; Need ultrasonic)
SMILES CC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN(C)C)C=C2)\C3=CC=CC=C3
Molecular Weight (g/mol) 371.51
Formula Weight 371.51
Percent Purity 99.2%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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