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Invitrogen™ TCF3 Monoclonal Antibody (401709)
Rat Monoclonal Antibody
Brand: Invitrogen™ MA561435
This item is not returnable.
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Description
Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.
TCF3 (E2A) is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.
Specifications
| TCF3 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| P15923 | |
| TCF3 | |
| E. coli-derived recombinant human TCF-3/E2A, Gly100-Glu500. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| Immunocytochemistry | |
| 401709 | |
| Unconjugated | |
| TCF3 | |
| A1; AA408400; AGM8; Alf2; AW209082; bHLHb21; class B basic helix-loop-helix protein 21; E12; E12/E47; E2A; E47; helix-loop-helix protein HE47; immunoglobulin enhancer-binding factor E12/E47; Immunoglobulin transcription factor 1; ITF1; Kappa-E2-binding factor; Me2; MGC129647; MGC129648; negative vitamin D response element-binding protein; NOL1-TCF3 fusion; Pan; Pan1; Pan2; pancreas specific transcription factor 1c; Ptf1c; TCF3; TCF-3; Tcfe2a; Transcription factor 3; transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); transcription factor 3 variant 3; transcription factor A1; transcription factor E2a; Transcription factor E2-alpha; transcription factor ITF-1; Transcription regulator Pan; VDIR; VDR interacting repressor; vitamin D receptor-interacting repressor | |
| Rat | |
| Protein A/G | |
| RUO | |
| 6929 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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