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Invitrogen™ TCL1A Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5148919
This item is not returnable.
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Description
Reconstitute at 0.2 mg/mL in sterile PBS.
Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha or TCR-beta regulatory elements (summarized by Virgilio et al., 1998). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (Laine et al., 2000).
Specifications
| TCL1A | |
| Polyclonal | |
| Unconjugated | |
| TCL1A | |
| oncogene TCL1; Oncogene TCL-1; Protein p14 TCL1; T cell lymphoma breakpoint 1; T-cell leukemia/lymphoma 1A; T-cell leukemia/lymphoma protein 1A; T-cell leukemia/lymphoma protein 1A (P14 TCL1 protein) (TCL1 oncogene) (TCL-1 protein); T-cell lymphoma breakpoint 1; T-cell lymphoma-1; T-cell lymphoma-1A; TCL1; TCL-1; TCL1A | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 8115 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Western Blot, Immunocytochemistry | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| P56279 | |
| TCL1A | |
| E. coli-derived recombinant human TCL1A, Met1-Asp114. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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