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Invitrogen™ Tenascin C Monoclonal Antibody (T2H5)

Description
This antibody recognizes tenascin C, a large hexametric extracellular matrix glycoprotein.
Tenascin is a high molecular weight, multifunctional, extracellular matrix glycoprotein expressed in association with mesenchymal-epithelial interactions during development and in the neovasculature and stroma of undifferentiated tumors (Erickson and Bourdon 1989). It has been described under a variety of names: cytotactin, hexabrachion protein, J1, myotendinous antigen (MI) and glioma mesenchymal extracellular matrix (GMEM). The tenascin molecule is a disulfide-linked hexamer. The expression of tenascin is associated with development and growth, both normal and pathological, whereas the distribution in normal adult tissue is restricted.
Specifications
Specifications
| Antigen | Tenascin C |
| Applications | Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | T2H5 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | TBS with 15 mM sodium azide; pH 8 |
| Gene | TNC |
| Gene Accession No. | P24821 |
| Gene Alias | 150-225; AI528729; C130033P17Rik; cytotactin; deafness, autosomal dominant 56; DFNA56; Glioma-associated-extracellular matrix antigen; GMEM; GP; GP 150-225; hexabrachion; hexabrachion (tenascin); Hxb; JI; MGC144208; MGC144209; MGC167029; Myotendinous antigen; neuronectin; Ten; Tenascin; tenascin C; Tenascin-C; tenascin-C additional domain 1; tenascin-C isoform 14/AD1/16; TN; tnc; TN-C |
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