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  7. tert-Butyldimethylchlorosilane, 97%, Thermo Scientific Chemicals

tert-Butyldimethylchlorosilane, 97%, Thermo Scientific Chemicals

Catalog Number 11474364
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Quantity:
5 g
25 g
100 g
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18162-48-6
C6H15ClSi
150.721
MFCD00000501
BCNZYOJHNLTNEZ-UHFFFAOYSA-N
tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride
28928
CHEBI:85071
tert-butyl-chloro-dimethylsilane
CC(C)(C)[Si](C)(C)Cl
This item is not returnable. View return policy
18162-48-6
C6H15ClSi
150.721
MFCD00000501
BCNZYOJHNLTNEZ-UHFFFAOYSA-N
tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride
28928
CHEBI:85071
tert-butyl-chloro-dimethylsilane
CC(C)(C)[Si](C)(C)Cl

Description

tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.

Solubility
Soluble in chloroform and ethyl acetate. Insoluble in water.

Notes
Moisture sensitive. Store in cool place. Incompatible with bases, metals, oxidizing agents and alcohols.
TRUSTED_SUSTAINABILITY
Boiling Point 124°C to 126°C
Melting Point 86°C to 89°C
Quantity 5 g
Linear Formula (CH3)3CSi(CH3)2Cl
UN Number UN2925
Beilstein 505999
Flash Point 22°C (72°F)
Solubility Information Soluble in chloroform and ethyl acetate. Insoluble in water.
Formula Weight 150.73
Percent Purity 97%
Odor Pungent
Sensitivity Moisture sensitive
Density 0.81
Chemical Name or Material tert-Butyldimethylchlorosilane
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Safety and Handling

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Product Identifier
  • tert-Butyldimethylchlorosilane
 Signal Word
  • Danger
 Hazard Category
  • LONG-TERM AQUATIC HAZARD Chronic 2
  • Serious eye damage/eye irritation Category 1
  • Flammable solid Category 2
  • Skin corrosion/irritation Category 1 A
 Hazard Statement
  • H228-Flammable solid.
  • H314-Causes severe skin burns and eye damage.
  • H318-Causes serious eye damage.
  • H411-Toxic to aquatic life with long lasting effects.
 Precautionary Statement
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.
 Supplemental information
  • MIXTURE LIST-Contains : Chloro(1,1-dimethylethyl)dimethyl-silane

RUO – Research Use Only

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