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Invitrogen™ Themis Monoclonal Antibody (701010)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561741
This item is not returnable.
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Description
Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.
Themis is a cytoplasmic protein that is essential for positive selection and the development of single-positive thymocytes. Highest levels of expression are found in CD4+CD8+ double-positive thymocytes, with lower expression found in mature T cells. In addition to Grb1, Themis has been found to associate with PLC gamma 1 and LAT and is quickly phosphorylated by SLP-76 following TCR signaling. There are 5 isoforms of mouse Themis that are produced as a result of alternative splicing.
Specifications
| Themis | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| Q8N1K5 | |
| Themis | |
| E. coli-derived recombinant human Themis, Ala2-Pro282. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| Flow Cytometry | |
| 701010 | |
| Unconjugated | |
| Themis | |
| bA325O24.3; bA325O24.4; C6orf190; C6orf207; E430004N04Rik; FLJ40584; Gasp; GRB2-associated protein; Grb2-associating protein; MGC163388; Protein THEMIS; Protein thylex; RGD1560849; signaling phosphoprotein specific for T cells; SPOT; THEMIS; thylex; thymocyte expressed molecule involved in selection; thymocyte selection associated; thymocyte selection pathway associated; thymocyte-expressed molecule involved in selection; Tsepa | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 387357 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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