missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ TIMD2 Monoclonal Antibody (222919)
Rat Monoclonal Antibody
Brand: Invitrogen™ MA561054
This item is not returnable.
View return policy
Description
Reconstitute at 0.5 mg/mL in sterile PBS.
TIM-2 recognizes T-cell immunoglobulin mucin 2, a transmembrane glycoprotein and member of the immunoglobulin superfamily, expressed by activated lymphocytes, developmentally in the 8-cell embryo and blastocyst, and preferentially up-regulated in Th2 cells and down-regulated in Th1 cells. Tim-2 acts as a negative regulator of Th2 cells, and is implicated to play a critical role in the development of atopic disease and other Th2-biased immune responses. Tim-2 also acts as a receptor for Semaphorin 4A, a transmembrane protein expressed on dendritic cells and B cells, which plays a role in the guidance of axonal migration during neuronal development, and has been shown to enhance T cell activation.
Specifications
| TIMD2 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| Q8R183 | |
| Timd2 | |
| Mouse myeloma cell line NS0-derived recombinant mouse TIM-2, His22-Asn229. | |
| 500 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a |
| Western Blot | |
| 222919 | |
| Unconjugated | |
| Timd2 | |
| AA816106; AU019358; AU019662; C78111; G9D3; T cell immunoglobulin and mucin domain containing 2; T-cell immunoglobulin and mucin domain containing 2; T-cell immunoglobulin and mucin domain-containing protein 2; T-cell immunoglobulin mucin receptor 2; T-cell membrane protein 2; Tim2; TIM-2; Timd2; TIMD-2 | |
| Rat | |
| Protein A/G | |
| RUO | |
| 171284 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction