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  6. TLK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

TLK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16892434 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16892434 20 μL 20µL
16882434 150 μL 150µL
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Product Code. 16892434 Supplier Proteintech Supplier No. 139791AP20UL

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Description

Rabbit Polyclonal Antibody

TLK2, a member of the Ser/Thr protein kinase family, is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. The TLK2 enzyme is cell-cycle regulated, with maximal activity in S-phase. It is inactivated by phosphorylation at Ser-750, potentially by CHK1. TLK2 heterodimerizes with TLK1. This nuclear protein is widely expressed, with presence in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle tissues, and in several adult cell lines.

Specifications

Antigen TLK2
Applications Western Blot, Immunofluorescence, Immunocytochemistry
Classification Polyclonal
Concentration 0.17 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TLK2
Gene Accession No. O55047, Q86UE8
Gene Alias PKU ALPHA, TLK2, tousled like kinase 2
Gene Symbols TLK2
Host Species Rabbit
Immunogen TLK2 Fusion Protein Ag5022
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11011, 24086, 303592
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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