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Invitrogen™ TNFAIP8 Recombinant Rabbit Monoclonal Antibody (24GB2315)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA557785
This item is not returnable.
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Description
TNFAIP8 Recombinant Monoclonal Antibody for Western Blot, Flow
TNFalpha-IP 8 (tumor necrosis factor, alpha-induced protein 8), also known as NFkappa B-inducible DED-containing protein (NDED), SCC-S2 or TNF-induced protein GG2-1, is a 198 amino acid cytoplasmic protein induced by NFkappa B and TNF. The induction of TNFalpha-IP 8 by TNF is dependent on the activation of NFkappa B. TNFalpha-IP 8 negatively mediates apoptosis and may also play a role in tumor progression. TNFalpha-IP 8 specifically inhibits caspase-8 activity, which results in the inhibition of BID cleavage and caspase-3 activation during TNF-mediated apoptosis. TNFalpha-IP 8 is expressed at high levels in thymus, bone marrow, lymph node, spleen, thyroid, placenta and various tumor tissues, as well as fetal lung, liver and kidney. TNFalpha-IP 8 is present as three isoforms produced by alternative splicing.
Specifications
| TNFAIP8 | |
| Recombinant Monoclonal | |
| Unconjugated | |
| Tnfaip8 | |
| AA987150; E130304C20Rik; ENSMUSG00000073567; GG2-1; Gm10539; head and neck tumor and metastasis-related protein; MDC3.13; MDC-3.13; Nded; NF-kappa-B-inducible DED-containing protein; SCC S2; SCCS2; SCC-S2; Ssc-2; TNF alpha induced protein 8; TNF alpha-induced protein 8; Tnfaip8; TNFalpha IP8; TNFalpha-IP 8; TNFalphaIP8; TNF-induced protein; TNF-induced protein GG2-1; Tumor necrosis factor alpha-induced protein 8; tumor necrosis factor, alpha induced protein 8; tumor necrosis factor, alpha-induced protein 8 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 106869, 25816, 307428 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot | |
| 24GB2315 | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O95379, Q921Z5 | |
| Tnfaip8 | |
| A synthesized peptide derived from human TNFAIP8 (aa 1-35). | |
| 20 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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