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Invitrogen™ ULK1 Recombinant Rabbit Monoclonal Antibody (24GB2195)
Rabbit Recombinant Monoclonal Antibody
146.00 € - 500.00 €
Specifications
| Antigen | ULK1 |
|---|---|
| Clone | 24GB2195 |
| Concentration | 0.33 mg/mL |
| Content And Storage | -20°C |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
30275535
|
Invitrogen™
MA557309 |
100 μL |
500.00 €
100µL |
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|
30275510
|
Invitrogen™
MA557310 |
20 μL |
146.00 €
20µL |
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Description
ULK1 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow
ULK1 is a serine/threonine protein kinase that plays critical role during initial stages of autophagy which is a vital response to nutrient starvation. The conserved C-terminal domain (CTD) of ULK1 controls the regulatory function and localization of the protein. Knockdown of ULK1 inhibits the autophagic response as well as inhibiting rapamycin-induced autophagy consistent with a role downstream of mTOR. ULK1 forms a complex with FIP200 and ATG13 and this complex is essential for starvation-induced autophagy. Both FIP200 and ATG13 are critical for correct localization of ULK1 to the pre-autophagosome and stability of ULK1 protein. ULK1 is phosphorylated by the mTOR pathway in a nutrient starvation-regulated manner.Specifications
| ULK1 | |
| 0.33 mg/mL | |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O70405, O75385 | |
| 22241, 360827, 8408 | |
| A synthesized peptide derived from human ULK1 (aa 950-1050). | |
| Antibody |
| 24GB2195 | |
| -20°C | |
| Recombinant Monoclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat | |
| ULK1 | |
| APG1; ATG 1; ATG1; ATG1 autophagy related 1 homolog; ATG1A; AU041434; Autophagy-related protein 1 homolog; C. elegans; EC:2.7.11.1; FLJ38455; hATG1; KIAA0722; mKIAA0722; Serine/threonine-protein kinase ULK1; serine/threonine-protein kinase Unc51.1; ULK 1; Ulk1; UNC 51; UNC51; unc-51 like autophagy activating kinase 1; unc-51 like kinase 1; Unc51.1; unc-51-like kinase 1 | |
| ULK1 | |
| Primary | |
| Affinity chromatography |
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