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Invitrogen™ ATP6V1C2 Polyclonal Antibody

Description
Antibody detects endogenous levels of total ATP6V1C2.
ATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.
Specifications
Specifications
| Antigen | ATP6V1C2 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | Atp6v1c2 |
| Gene Accession No. | Q8NEY4 |
| Gene Alias | 1110038G14Rik; Atp6c2; Atp6v1c2; ATPase H+ transporting V1 subunit C2; ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2; ATPase, H+ transporting, lysosomal V1 subunit C2; ATPase, H+ transporting, V1 subunit C, isoform 2; vacuolar H+ ATPase C2; vacuolar proton pump subunit C 2; V-ATPase C2 subunit; V-ATPase subunit C 2; VMA5; V-type ATPase C2 subunit a isoform; V-type proton ATPase subunit C 2 |
| Gene Symbols | Atp6v1c2 |
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