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  6. Invitrogen™ VISTA Monoclonal Antibody (MIH64), NovaFluor™ Yellow 610, eBioscience™, Invitrogen™

Invitrogen™ VISTA Monoclonal Antibody (MIH64), NovaFluor™ Yellow 610, eBioscience™, Invitrogen™

Product Code. p-200025745
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100 μg
25 μg
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100µg
25µg
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Product Code. Quantity unitSize
30055883 100 μg 100µg
30056051 25 μg 25µg
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Product Code. 30055883 Supplier Invitrogen™ Supplier No. M035T03Y03A

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Description

Rat Monoclonal Antibody

VISTA (V-domain Ig containing suppressor of T-cell activation), also known as B7-H5 or PD-1H, is a product of the VSIR gene. Although VISTA bears sequence homology to PD-L1 it has a different expression pattern. In both mouse and humans, VISTA is expressed predominantly on hematopoietic cells with the highest densities on myeloid cells, and lower levels on T cells. It is usually absent on B cells. VISTA expressed by antigen presenting cells has been shown to directly suppress proliferation and cytokine production of CD4 and CD8 T cells, making it a target for cancer immunotherapy. The reported ligands of VISTA include CD28H, VSIG-3 and VSIG-8.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VISTA
Applications Flow Cytometry
Classification Monoclonal
Clone MIH64
Concentration 0.1 mg/mL
Conjugate NovaFluor Yellow 610
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene VSIR
Gene Accession No. Q9D659
Gene Alias 4632428N05Rik; B7H5; B7-H5; C10orf54; C1H10orf54; C28H10orf54; C4H10orf54; chromosome 10 open reading frame 54; DD1alpha; Death Domain1alpha; Dies1; differentiation of ESCs 1; GI24; PD-1H; PDCD1 homolog; PD-H1; platelet receptor Gi24; PP2135; RIKEN cDNA 4632428N05 gene; SISP1; sisp-1; Stress-induced secreted protein-1; UNQ730/PRO1412; V-domain Ig suppressor of T cell activation; VISTA; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor; VSIR; V-type immunoglobulin domain-containing suppressor of T-cell activation
Gene Symbols VSIR
Host Species Rat
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 74048
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG2a κ
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