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Tocris Bioscience™ VU 0422288
Selective group III mGlu positive allosteric modulator
Brand: Tocris Bioscience™ 5378/10
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Description
VU 0422288 is a group III mGlu receptor positive allosteric modulator (EC50 values are 108, 125 and 146 nM for mGlu4, mGlu8 and mGlu7 respectively). Exhibits selectivity over a panel of 68 other GPCRs, ion channels and transporters. Potentiates mGlu7-mediated reductions in excitatory post synaptic potentials in hippocampal slices.Specifications
| VU 0422288 | |
| N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide | |
| Soluble to 100mM in DMSO | |
| Bioactive Small Molecule |
| 1630936-95-6 | |
| 10 mg | |
| Solid |
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