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Y16, MedChemExpress

Product Code. 16445278
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Product Code. 16445278 Supplier Medchem Express Supplier No. HY12649

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Description

MedChemExpress Y16 is a specific inhibitor of Leukemia-associated Rho guanine nucleotide exchange factor (LARG) with a Kd value of 76 nM. Y16 is active in blocking the interaction of LARG and related G-protein-coupled Rho GEFs with RhoA. Y16 shows no detectable effect on other diffuse B-cell lymphoma (Dbl) family Rho GEFs, Rho effectors, or a RhoGAP.

Y16 is a specific inhibitor of Leukemia-associated Rho guanine nucleotide exchange factor (LARG) with a Kd value of 76 nM. Y16 is active in blocking the interaction of LARG and related G-protein-coupled Rho GEFs with RhoA. Y16 shows no detectable effect on other diffuse B-cell lymphoma (Dbl) family Rho GEFs, Rho effectors, or a RhoGAP.

Specifications

Chemical Name or Material Y16
CAS 429653-73-6
Color Red
Purity Grade Notes Research
Molecular Formula C24H20N2O3
Quantity 10 mg
Solubility Information DMSO : 25 mg/mL (65.03 mM; Need ultrasonic)
SMILES O=C(N1)/C(C(N1C2=CC=CC=C2)=O)=C\C3=CC(OCC4=CC(C)=CC=C4)=CC=C3
Molecular Weight (g/mol) 384.43
Formula Weight 384.43
Percent Purity 97.42%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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