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ZFYVE21 Monoclonal Antibody (OTI2B12), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA505606
This item is not returnable.
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Description
ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.Specifications
| ZFYVE21 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q9BQ24 | |
| ZFYVE21 | |
| Full length human recombit protein of human ZFYVE21 produced in HEK293T cell. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI2B12 | |
| Unconjugated | |
| ZFYVE21 | |
| HCVP7TP1, ZF21 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 79038 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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