CAS RN 1346547-00-9

CAS RN 1346547-00-9

IUPAC Name: N-(5-fluoro-1H-indazol-3-yl)-6-(2-methylpropane-2-sulfonyl)quinolin-4-amine

Synonyms: N-(5-fluoro-1H-indazol-3-yl)-6-(2-methylpropane-2-sulfonyl)quinolin-4-amine

Molecular Weight (g/mol): 398.46

Molecular Formula: C20H19FN4O2S

InChi Key: XLOGLWKOHPIJLV-UHFFFAOYSA-N

SMILES: CC(C)(C)S(=O)(=O)C1=CC=C2N=CC=C(NC3=NNC4=CC=C(F)C=C34)C2=C1

Molecular Weight (g/mol)

1 – 3 of 3 results

1

Thermo Scientific™ GSK583, 95%

Pricing and Availability

2

Tocris Bioscience™ GSK 583

Potent RIP2 kinase inhibitor; orally bioavailable and cell permeable

Pricing and Availability
Specifications

CAS	1346547-00-9
Purity	98%
Chemical Name or Material	6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine
Recommended Storage	Store at -20°C
Molecular Formula	C₂₀H₁₉FN₄O₂S

3

GSK583, MedChemExpress

MedChemExpress GSK583 is a highly potent, orally active and selective inhibitor of RIP2 Kinase, with IC50 of 5 nM. GSK583 inhibits both TNF-α and IL-6 production with an IC50 value of 200 nM.

ENCOMPASS_PREFERRED

Pricing and Availability
Specifications

Molecular Weight (g/mol)	398.45
Color	Yellow
Physical Form	Solid
Chemical Name or Material	GSK583
Grade	Research
SMILES	FC1=CC2=C(NN=C2NC3=CC=NC4=CC=C(S(=O)(C(C)(C)C)=O)C=C34)C=C1
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.74%
CAS	1346547-00-9
Solubility Information	DMSO : ≥ 100 mg/mL (250.97 mM)
Health Hazard 1	H302∣H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₁₉FN₄O₂S
Formula Weight	398.45