CAS RN 139504-50-0
CAS RN 139504-50-0
Mertansine, TRC
CAS: 139504-50-0 Molecular Formula: C35H48ClN3O10S Molecular Weight (g/mol): 738.29 Synonym: N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine,DM 1,Maytansinoid DM 1,N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine SMILES: O=C(C[C@H](OC([C@H](C)N(C)C(CCS)=O)=O)[C@@]([C@H]1[C@@H]2C)(O1)C)N(C)C3=CC(C/C(C)=C/C=C/[C@@H](OC)[C@]4(O)NC(O[C@H]2C4)=O)=CC(OC)=C3Cl
Mertansine, MedChemExpress
MedChemExpress Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC).