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CAS RN 162635-04-3

OOOOHOOOOOOHOHOOHOOON(S)(R)(R)(R)(S)H3C(S)(R)(R)H3C(R)H3CCH3(S)H3C(R)CH3H3C(R)CH3(R)(S)CH3CH3CH3HHH(?)(?)(?)(?)

CAS RN 162635-04-3

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1

Thermo Scientific™ Temsirolimus, 99+%

Assay: ≥99% CAS: 162635-04-3 Formula Weight: 1030.29g/mol Content And Storage: -30°C to -10°C Format: Powder For Use With (Application): A Rapamycin derivative with anti-cancer activity that inhibits mTOR Description: White to Off-white

Assay ≥99%
Content And Storage -30°C to -10°C
Description White to Off-white
Format Powder
CAS 162635-04-3
For Use With (Application) A Rapamycin derivative with anti-cancer activity that inhibits mTOR
Formula Weight 1030.29g/mol
2

Temsirolimus (~90%), TRC

CAS: 162635-04-3 Molecular Formula: C56 H87 N O16 Molecular Weight (g/mol): 1030.29 Synonym: Rapamycin, 42-[3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate],40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin,CCI 779,Temsirolimus,Temsorolimus,Torisel,WAY-CCI 779 SMILES: CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(/C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(/C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)OC)CC[C@H]1OC(=O)C(C)(CO)CO

CAS 162635-04-3
Molecular Weight (g/mol) 1030.29
SMILES CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(/C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(/C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)OC)CC[C@H]1OC(=O)C(C)(CO)CO
Synonym Rapamycin, 42-[3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate],40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin,CCI 779,Temsirolimus,Temsorolimus,Torisel,WAY-CCI 779
Molecular Formula C56 H87 N O16
3

Temsirolimus, MedChemExpress

MedChemExpress Temsirolimus is an inhibitor of mTOR with an IC50 of 1.76 μM. Temsirolimus activates autophagy and prevents deterioration of cardiac function in animal model.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 1030.29
Color White
Physical Form Powder
Chemical Name or Material Temsirolimus
Grade Research
SMILES O=C([C@@]1(O)[C@@H](CC[C@@H](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@@H](C)C([C@@H]([C@@H](/C(C)=C/[C@H]2C)O)OC)=O)C)OC)O1)C)C(N3CCCC[C@H]3C(O[C@@H](CC2=O)[C@@H](C[C@H]4C[C@H]([C@H](OC(C(C)(CO)CO)=O)CC4)OC)C)=O)=O
For Use With (Application) Cancer-Kinase/protease
Percent Purity 98.0%
CAS 162635-04-3
Solubility Information DMSO : 250 mg/mL (242.65 mM; Need ultrasonic) ∣Ethanol : 200 mg/mL (194.12 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
Health Hazard 1 H302∣H315∣H319∣H335
Synonym CCI-779
Purity Grade Notes Research
Recommended Storage 4°C, protect from light, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light, stored under nitrogen)
Shelf Life 4°C, protect from light, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light, stored under nitrogen)
Molecular Formula C56H87NO16
Formula Weight 1030.29