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R&D Systems™ Pan Caspase Inhibitor Z-VAD-FMK
Used as cell-permeable, irreversible inhibitor of caspase activity. R&D Systems Pan Caspase Inhibitor Z-VAD-FMK binds to the active site of activated proteases irreversibly and inhibits apoptosis.
Tocris Bioscience™ Aprotinin
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Competitive serine protease inhibitor
Tocris Bioscience™ ATPgammaS tetralithium salt
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Non-selective P2 agonist; analog of ATP (Cat. No. 3245)
Tocris Bioscience™ FK 506
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Potent calcineurin inhibitor; immunosuppressant
Tocris Bioscience™ PRT 4165
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Inhibitor of Bmi1/Ring1A; blocks histone H2A ubiquitination
| Inhibitors | PRT 4165 |
|---|---|
| Product Type | PRT 4165 |
| Molecular Weight (g/mol) | 235.24 |
| Purity | >99% |
Tocris Bioscience™ GSK 2606414
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This product offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Potent and selective PERK inhibitor; orally bioavailable
| Inhibitors | GSK 2606414 |
|---|---|
| Product Type | GSK 2606414 |
| Molecular Weight (g/mol) | 451.44 |
| Purity | >99% |
Tocris Bioscience™ VO-OHpic
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This product offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Potent PTEN inhibitor
| Inhibitors | VO-OHpic |
|---|---|
| Product Type | VO-OHpic |
| Molecular Weight (g/mol) | 361.16 |
| Purity | >98% |
Tocris Bioscience™ ML 337
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This product offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Selective negative allosteric modulator of mGlu3
| Inhibitors | ML 337 |
|---|---|
| Product Type | ML 337 |
| Molecular Weight (g/mol) | 353.39 |
| Purity | >98% |
Tocris Bioscience™ WH-4-023
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Potent and selective Lck and Src inhibitor; also inhibits SIK
| Inhibitors | WH-4-023 |
|---|---|
| Product Type | WH-4-023 |
| Molecular Weight (g/mol) | 568.67 |
| Purity | >98% |
Tocris Bioscience™ BTB1
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Selective and ATP-competitive Kif18A inhibitor
| Inhibitors | BTB1 |
|---|---|
| Product Type | BTB1 |
| Molecular Weight (g/mol) | 297.71 |
| Purity | >99% |
Tocris Bioscience™ KHS 101 hydrochloride
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This product offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Selective inducer of neuronal differentiation in hippocampal neural progenitors
| Inhibitors | KHS 101 hydrochloride |
|---|---|
| Product Type | KHS 101 hydrochloride |
| Molecular Weight (g/mol) | 375.92 |
| Purity | >98% |
Tocris Bioscience™ (S)-PFI 2 hydrochloride
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Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)
Tocris Bioscience™ A 366
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Potent and selective G9a/GLP inhibitor
| Inhibitors | A 366 |
|---|---|
| Product Type | A 366 |
| Molecular Weight (g/mol) | 329.44 |
| Purity | >98% |
Tocris Bioscience™ IWP 4
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This product offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Potent inhibitor of Wnt/β-catenin signaling
| Inhibitors | IWP 4 |
|---|---|
| Product Type | IWP 4 |
| Molecular Weight (g/mol) | 496.62 |
| Purity | >98% |
Tocris Bioscience™ GSK 2830371
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This product offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Potent and selective allosteric inhibitor of Wip1 phosphatase
| Inhibitors | GSK 2830371 |
|---|---|
| Product Type | GSK 2830371 |
| Molecular Weight (g/mol) | 461.02 |
| Purity | >98% |