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R&D Systems™ Pan Caspase Inhibitor Z-VAD-FMK
Used as cell-permeable, irreversible inhibitor of caspase activity. R&D Systems Pan Caspase Inhibitor Z-VAD-FMK binds to the active site of activated proteases irreversibly and inhibits apoptosis.
Tocris Bioscience™ Aprotinin
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Competitive serine protease inhibitor
Tocris Bioscience™ ATPgammaS tetralithium salt
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Non-selective P2 agonist; analog of ATP (Cat. No. 3245)
Tocris Bioscience™ FK 506
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Potent calcineurin inhibitor; immunosuppressant
Tocris Bioscience™ PRT 4165
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Inhibitor of Bmi1/Ring1A; blocks histone H2A ubiquitination
| Inhibitors | PRT 4165 |
|---|---|
| Product Type | PRT 4165 |
| Molecular Weight (g/mol) | 235.24 |
| Purity | >99% |
Tocris Bioscience™ GSK 2606414
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This product offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Potent and selective PERK inhibitor; orally bioavailable
| Inhibitors | GSK 2606414 |
|---|---|
| Product Type | GSK 2606414 |
| Molecular Weight (g/mol) | 451.44 |
| Purity | >99% |
Tocris Bioscience™ (S)-PFI 2 hydrochloride
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Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)
Tocris Bioscience™ GSK 2830371
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Potent and selective allosteric inhibitor of Wip1 phosphatase
| Inhibitors | GSK 2830371 |
|---|---|
| Product Type | GSK 2830371 |
| Molecular Weight (g/mol) | 461.02 |
| Purity | >98% |
Tocris Bioscience™ WH-4-023
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Potent and selective Lck and Src inhibitor; also inhibits SIK
| Inhibitors | WH-4-023 |
|---|---|
| Product Type | WH-4-023 |
| Molecular Weight (g/mol) | 568.67 |
| Purity | >98% |
Tocris Bioscience™ A 366
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Potent and selective G9a/GLP inhibitor
| Inhibitors | A 366 |
|---|---|
| Product Type | A 366 |
| Molecular Weight (g/mol) | 329.44 |
| Purity | >98% |
Tocris Bioscience™ LIMKi 3
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Potent LIM kinase inhibitor; antitumor
Tocris Bioscience™ NS 9283
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Positive allosteric modulator of α4β2 nAChRs
| Inhibitors | NS 9283 |
|---|---|
| Product Type | NS 9283 |
| Molecular Weight (g/mol) | 248.24 |
| Purity | >99% |
Tocris Bioscience™ TC-S 7006
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Potent and selective Tpl2 (Cot; MAP3K8) inhibitor
| Inhibitors | TC-S 7006 |
|---|---|
| Product Type | TC-S 7006 |
| Molecular Weight (g/mol) | 404.83 |
| Purity | >99% |
Tocris Bioscience™ CVT 10216
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Potent and selective ALDH2 inhibitor
| Inhibitors | CVT 10216 |
|---|---|
| Product Type | CVT 10216 |
| Molecular Weight (g/mol) | 465.48 |
| Purity | >98% |
Tocris Bioscience™ Ro 48-8071 fumarate
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2,3-Oxidosqualene cyclase (OSC) inhibitor; blocks cholesterol synthesis
| Inhibitors | Ro 48-8071 fumarate |
|---|---|
| CAS | 189197-69-1 |
| Product Type | Ro 48-8071 fumarate |
| Molecular Weight (g/mol) | M.W. (Observed): 564.44 |
| Purity | 99% |
| Recommended Storage | 4°C |
| Molecular Formula | (4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone |