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5-Azacytidine, 98%, Thermo Scientific™

Causes DNA demethylation or hemi-demethylation; a powerful mutagen

101.00 € - 372.99 €

Chemical Identifiers

CAS 320-67-2
Molecular Formula C8H12N4O5
Molecular Weight (g/mol) 244.207
MDL Number MFCD00006539
InChI Key NMUSYJAQQFHJEW-KVTDHHQDSA-N
Synonym 5-azacytidine, azacitidine, ladakamycin, azacytidine, vidaza, mylosar, azacitidina, azacitidinum, 5-azacitidine, azacitidinum inn-latin
PubChem CID 9444
ChEBI CHEBI:2038
IUPAC Name 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
SMILES C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N
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15426239
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Thermo Scientific Alfa Aesar
J64159.03
1g
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15436239
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Thermo Scientific Alfa Aesar
J64159.06
5g
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380.00 €
372.99 € / 5g
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Description

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.

Solubility
Soluble in water.

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
Specifications

Chemical Identifiers

320-67-2
244.207
NMUSYJAQQFHJEW-KVTDHHQDSA-N
9444
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
C8H12N4O5
MFCD00006539
5-azacytidine, azacitidine, ladakamycin, azacytidine, vidaza, mylosar, azacitidina, azacitidinum, 5-azacitidine, azacitidinum inn-latin
CHEBI:2038
C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N

Specifications

320-67-2
MFCD00006539
14,890
Soluble in water.
C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N
244.207
CHEBI:2038
98%
C8H12N4O5
620461
5-azacytidine, azacitidine, ladakamycin, azacytidine, vidaza, mylosar, azacitidina, azacitidinum, 5-azacitidine, azacitidinum inn-latin
NMUSYJAQQFHJEW-KVTDHHQDSA-N
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
9444
244.2
5-Azacytidine
Videos
Safety and Handling

Safety and Handling

GHS H Statement
H340-H350-H302
May cause genetic defects.
May cause cancer.
Harmful if swallowed.

P201-P202-P264b-P270-P281-P301+P312-P308+P313-P330-P501c

H302-H340-H350

missing translation for 'einecsNumber' : 206-280-2

missing translation for 'rtecsNumber' : XZ3017500

missing translation for 'tsca' : No

Recommended Storage : Store at -20°C

Product Identifier
  • 5-Azacytidine

Signal Word
  • Danger

Hazard Category
  • Acute toxicity Category 4
  • Carcinogenicity Category 1B
  • Germ cell mutagenicity Category 1B

Hazard Statement
  • H302-Harmful if swallowed.
  • H340-May cause genetic defects.
  • H350-May cause cancer.

Precautionary Statement
  • P201-Obtain special instructions before use.
  • P264-Wash face, hands and anyexposed skin thoroughly after handling.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.

Supplemental information
  • MIXTURE LIST-Contains : 5-Azacytidine

SDS
Documents

Documents

Product Certifications

RUO – Research Use Only

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