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CD184 Rat anti-Mouse, FITC, Clone: 2B11/CXCR4, BD
Rat Monoclonal Antibody
Brand: BD Biosciences 561735
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Description
The monoclonal antibody 2B11/CXCR4 reacts with the mouse CD184, which is also known as CXC chemokine receptor, CXCR4. CXCR4 (previously known as fusin, LESTR and HUMSTR), a seven-transmembrane, G-protein-coupled receptor, is the specific receptor for CXC chemokines, SDF-1/CXCL12. Mouse CXCR4 showed 91% homology at amino acid level with human CXCR4. The CXCR4 is widely expressed by hematopoietic and non hematopoietic cell types including PMN, monocytes, T cells, B cells, CD34+ progenitor cells, endothelial cells, neurons and astrocytes. The human CXCR4 is used by T-tropic HIV-1 as a co-receptor for viral entry. The mouse CXCR4 gene has been mapped to chromosome 1. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Host Species: Rat
Clone: 2B11/CXCR4
Isotype: IgG2b κ
Species Reactivity: Mouse
Immunogen: GST-NCXCR4 fusion protein
Flow Cytometry
Specifications
| CD184 | |
| Monoclonal | |
| 0.5mg/mL | |
| CXCR4, C-X-C chemokine receptor type 4; Fusin; LESTR; PB-CKR; Sdf1r | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Mouse | |
| IgG2b κ |
| Flow Cytometry | |
| 2B11/CXCR4 | |
| FITC | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| GST-NCXCR4 fusion protein | |
| 25 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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