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CD2 Mouse anti-Human, BUV395, Clone: RPA-2.10, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 563820
This item is not returnable.
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Description
The RPA-2.10 monoclonal antibody specifically binds to CD2. CD2 is a 50 kDa single-chain transmembrane glycoprotein, also known as LFA-2 or the receptor for sheep erythrocytes. CD2 belongs to the immunoglobulin superfamily of proteins along with its ligand LFA-3, CD58. It is present on about 80-90% of human peripheral blood lymphocytes, greater than 95% of thymocytes, all T lymphocytes that form E-rosettes and a subset of NK cells. CD2 plays a role in T-cell signaling and in lymphocyte adhesion.
The antibody was conjugated to BD Horizon™ BUV395 which has been exclusively developed by BD Biosciences as an optimal dye for use on a 355nm laser equipped instrument. With an Ex Max at 348nm and an Em Max at 395nm, this dye has virtually no spillover into any other detector. BD Horizon™ BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.
Specifications
| CD2 | |
| Monoclonal | |
| Brilliant Ultraviolet 395 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human Phytohemagglutinin-treated Lymphoblast | |
| 25 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| RPA-2.10 | |
| LFA-2; Lymphocyte function antigen-2; T11/Leu-5; Rosette receptor | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG1 κ |
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