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Connexin-43 Mouse, Unlabeled, Clone: 2, BD
Mouse Monoclonal Antibody
178.69 € - 355.24 €
Specifications
| Antigen | Connexin-43 |
|---|---|
| Clone | 2 |
| Concentration | 250μg/mL |
| Applications | Western Blot |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15895229
|
BD Biosciences
610061 |
50 μg |
 187.00 € 178.69 € / 1 set Save 8.31 € 4% Off |
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|
15805239
|
BD Biosciences
610062 |
150 μg |
371.00 € 355.24 € / 1 set Save 15.76 € 4% Off |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Gap junctions are intercellular protein pores. They enable cell-to-cell communication by allowing passage of ions and other small molecules. The subunits of gap junction channels are assembled from a family of proteins called connexins. Individual connexin molecules join to make hexameric hemichannels termed connexons; these structures dock to connexons on neighboring cells, forming gap junction pores. Connexin-43 is a member of the connexin family possessing four transmembrane regions, with cytoplasmic amino and carboxyl terminals. It undergoes rapid turnover in the cell and its monomers may reside in the ER/Golgi network, forming a reservoir available for assembly upon
degradation of existing connexin-43 channels. In addition, it is believed that phosphorylation of connexin-43 plays a regulatory role both in the assembly of connexons and in gating activity at the gap junction.
Host Species: Mouse
Clone: 2
Isotype: IgG2
Species Reactivity: Rat
Immunogen: Rat Connexin-43 aa. 252-270
Formula Weight [Chemical]: 43kDa
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Specifications
| Connexin-43 | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified |
| 2 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Canine, Chicken, Human, Mouse, Rat | |
| Rat Connexin-43 aa. 252-270 | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
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