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DLP1 Mouse, Unlabeled, Clone: 8, BD

Mouse Monoclonal Antibody

186.18 € - 323.14 €

Specifications

Antigen DLP1
Clone 8
Concentration 250μg/mL
Applications Western Blot
Classification Monoclonal
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15865799
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BD Biosciences
611112
50 μg
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194.00 €
186.18 € / 1 set
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15875799
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BD Biosciences
611113
150 μg
ONLINE EXCLUSIVE PRICE
336.00 €
323.14 € / 1 set
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Description

Description

Dynamins, phosphoproteins with intrinsic GTPase activities, play an important role during early endocytosis. The GTPase activity is stimulated in vitro by microtubules, SH3 domain containing-proteins, and Protein Kinase (PKC)- mediated phosphorylation. Although highly related, dynamins are differentially expressed in an organism. For instance, dynamin I is found only in the nervous system, dynamin II is ubiquitously expressed, and dynamin III is located in lung, testis and brain. Due to four alternative splicing products for each of the dynamins, the dynamin family contains at least 12 different members. The Dynamin Like Protein-1 (DLP1) is a new member of the dynamin family of proteins. DLP1 (also known as DVLP) is widely expressed as two alternatively spliced products, each with different tissue expression patterns. The larger product is about 84kDa and reportedly found only in the brain, whereas the 79kDa product is ubiquitously expressed. Unlike dynamins I-III which co-localize with endocytotic vesicles, DLP1 is found aligned with microtubules and with the endoplasmic reticulum, suggesting a secretory function for this novel protein.

Host Species: Mouse
Clone: 8
Isotype: IgG1
Species Reactivity: Rat
Immunogen: Rat DLP1 aa. 601-722
Formula Weight [Chemical]: 79-84kDa

Immunofluorescence, Western Blotting

Specifications

Specifications

DLP1
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG1
Affinity Purified
Dynamin Like Protein-1; DVLP
8
Western Blot
Unconjugated
RUO
Canine, Human, Mouse, Rat
Rat DLP1 aa. 601-722
Primary
Store undiluted at -20°C.
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