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  6. HLA-DR Mouse anti-Human, Brilliant Violet 605, Clone: G46-6, BD
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HLA-DR Mouse anti-Human, Brilliant Violet 605, Clone: G46-6, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 562844

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Product Code. 15862289

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Description

Description

The G46-6 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen. HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells: B cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.

For optimal and reproducible results, BD Horizon Brilliant Stain Buffer should be used anytime two or more BD Horizon Brilliant dyes are used in the same experiment. Fluorescent dye interactions may cause staining artifacts which may affect data interpretation. The BD Horizon Brilliant Stain Buffer was designed to minimize these interactions. More information can be found in the Technical Data Sheet of the BD Horizon Brilliant Stain Buffer (Cat. No. 563794).

TRUSTED_SUSTAINABILITY
Specifications

Specifications

HLA-DR
Monoclonal
Brilliant Violet 605
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Affinity Purified
RUO
Baboon, Cynomolgus, Human, Rhesus Monkey
IgG2a κ
Flow Cytometry
G46-6
MHC class II antigen; HLA class II histocompatibility antigen
Mouse
25 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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