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HLA-DR Mouse anti-Human, Brilliant Violet 605, Clone: G46-6, BD

Mouse Monoclonal Antibody

218.28 € - 500.76 €

Specifications

Antigen HLA-DR
Clone G46-6
Applications Flow Cytometry
Classification Monoclonal
Conjugate Brilliant Violet 605
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BD Biosciences
562844
25 Tests
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15872289
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BD Biosciences
562845
100 Tests
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515.00 €
500.76 € / Each
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Description

Description

The G46-6 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen. HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells: B cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.

For optimal and reproducible results, BD Horizon Brilliant Stain Buffer should be used anytime two or more BD Horizon Brilliant dyes are used in the same experiment. Fluorescent dye interactions may cause staining artifacts which may affect data interpretation. The BD Horizon Brilliant Stain Buffer was designed to minimize these interactions. More information can be found in the Technical Data Sheet of the BD Horizon Brilliant Stain Buffer (Cat. No. 563794).

Specifications

Specifications

HLA-DR
Flow Cytometry
Brilliant Violet 605
RUO
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
G46-6
Monoclonal
Mouse
Baboon, Cynomolgus, Human, Rhesus Monkey
IgG2a κ
Affinity Purified
MHC class II antigen; HLA class II histocompatibility antigen
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