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CD45RA Mouse anti-Rat, FITC, Clone: OX-33, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 554883
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Description
The OX-33 antibody reacts with a high-molecular-weight form of CD45 found only on B lymphocytes. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family: Its intracellular (COOH-terminal) region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated A, B, and C, respectively), plus differing levels of glycosylation. The CD45 isoforms detected in the rat are cell type-, maturation-, and activation state-specific. The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.
This antibody isroutinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Specifications
| CD45RA | |
| Monoclonal | |
| 0.5mg/mL | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Leukocyte common antigen purified from rat splenocytes | |
| 0.5 mg | |
| Immunology | |
| Rat | |
| IgG1 κ |
| Flow Cytometry | |
| OX-33 | |
| FITC | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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