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Cytokeratin 17 Antibody (E3 (same as Ks17.E3)), Novus Biologicals™
Mouse Monoclonal Antibody has been used in 2 publications
286.00 € - 595.00 €
Specifications
| Antigen | Cytokeratin 17 |
|---|---|
| Clone | E3 (same as Ks17.E3) |
| Concentration | 0.2 mg/ml |
| Dilution | Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml |
| Applications | Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin) |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18497151
|
Novus Biologicals
NBP2-29421-20ug |
20 ug |
286.00 €
21µg |
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|
18083624
|
Novus Biologicals
NBP2-29421 |
0.1 mg |
595.00 €
0.10mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Cytokeratin 17 Monoclonal specifically detects Cytokeratin 17 in Human, Rat, Porcine, Bovine, Goat samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.Specifications
| Cytokeratin 17 | |
| 0.2 mg/ml | |
| Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin) | |
| Unconjugated | |
| Mouse | |
| Cancer | |
| Q04695 | |
| 3872 | |
| Cytoskeletal fraction of rat colon epithelium (Uniprot: Q04695) | |
| Primary | |
| Store at 4C. | |
| 46 kDa |
| E3 (same as Ks17.E3) | |
| Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml | |
| Monoclonal | |
| Purified | |
| RUO | |
| Human, Rat, Pig, Bovine, Goat | |
| 39.1, CK-17, cytokeratin-17, K17, keratin 17, keratin, type I cytoskeletal 17, keratin-17, PC, PC2, PCHC1 | |
| KRT17 | |
| IgG2b κ | |
| Protein A or G purified | |
| Cytokeratin 17 (CK17) is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as 'epithelial stem cell' marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer, intestinal vs. pancreatobiliary, is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype. |
For Research Use Only
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