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p53 Ab-4, Mouse Monoclonal Antibody,Lab Vision™ Epredia™
Achieve accurate, reproducible results with the Epredia™ p53 Ab-4, Mouse Monoclonal Antibody.
Brand: Epredia MS-182-PABX
This item is not returnable.
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Description
p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.Host Species: Mouse
Clone: PAb 122
Isotype: IgG2b/κ
Species Reactivity: Human, Monkey, Mouse, Rat, and Hamster. Others not known.
Epitope: aa 370-378
Immunogen: SV40-transformed mouse B4 cells
Molecular Weight: 53kDa
Positive Control: MDA-231 cells
Cellular Localization: Nuclear
Recommended for:
- Western Blotting
- Immunofluorescence
- Immunoprecipitation (Denatured verified)
- Flow Cytometry
Note:
USA: RUO; Int'l: RUO
Specifications
| p53 Ab-4 | |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 200 μL | |
| Cancer and Tumor Biology | |
| Hamster, Human, Mouse, Non-human Primate, Rat | |
| IgG2b κ |
| Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot | |
| PAb 122 | |
| Unconjugated | |
| SV40-transformed mouse B4 cells | |
| RUO | |
| Primary | |
| Concentrated |
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