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Invitrogen™ Phospho-Cyclin B1 (Ser126) Recombinant Rabbit Monoclonal Antibody (24GB4310)
Rabbit Recombinant Monoclonal Antibody
198.00 € - 564.00 €
Specifications
| Antigen | Phospho-Cyclin B1 (Ser126) |
|---|---|
| Clone | 24GB4310 |
| Content And Storage | -20°C |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
30275181
|
Invitrogen™
MA557572 |
100 μL |
564.00 €
100µL |
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|
30275911
|
Invitrogen™
MA557573 |
20 μL |
198.00 €
20µL |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Phospho-Cyclin B1 (Ser126) Recombinant Monoclonal Antibody for Western Blot, ICC/IF
Cyclins bind to and regulate the activity of the Cyclin dependent protein kinases (CDKs). Cyclin B1 or CCNB1 is a regulatory protein involved in mitosis. It is essential for the control of the cell cycle at the G2/M transition. Cyclin B1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. Cyclin B1 is not ubiquitinated during G2/M phase, resulting in its steady accumulation during G2 phase, followed by abrupt APC dependent destruction at the end of mitosis. Destruction of Cyclin B1 is required for cell cycle progression. Cyclin B1 is overexpressed in various cancers, including breast, prostate, and non-small cell lung cancer.Specifications
| Phospho-Cyclin B1 (Ser126) | |
| -20°C | |
| Recombinant Monoclonal | |
| Liquid | |
| IgG | |
| Human | |
| Ccnb1 | |
| Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023 | |
| Ccnb1 | |
| Primary | |
| Affinity chromatography |
| 24GB4310 | |
| Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P14635 | |
| 891 | |
| A synthesized peptide derived from human Phospho-Cyclin B1 (Ser126) (aa 120-133). | |
| Antibody |
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