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Invitrogen™ PLSCR1 Recombinant Rabbit Monoclonal Antibody (24GB1550)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA557580
This item is not returnable.
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Description
PLSCR1 Recombinant Monoclonal Antibody for Western Blot, Flow
The calcium-dependent plasma membrane protein phospholipid scramblase 1 (PLSCR1) contributes to the transbilayer movement of phosphatidylserine and other membrane phospholipids upon influx of calcium into the cytosol. This movement results in plasma membrane phospholipid remodelling and surface exposure of phosphatidylserine in injured or apoptotic cells, which leads to cell death. Interferons and other cytokines induce expression of PLSCR1, implying that PLSCR1 also functions in cytokine signaling pathways. EGF stilmulation results in tyrosine phosphorylation of PLSCR1 on tyrosines 69 and 74, which allows it to interact with Shc, and thereby connecting Src kinase activation to stimulation of the EGF receptor.
Specifications
| PLSCR1 | |
| Recombinant Monoclonal | |
| Unconjugated | |
| PLSCR1 | |
| ca(2+)-dependent phospholipid scramblase 1; Erythrocyte phospholipid scramblase; MmTRA1a; MmTRA1b; NOR1; Phospholipid scramblase 1; phospholipid scramblase 2; PL scramblase 1; Plscr1; Tra1; Tra1a; Tra1b; transplantability-associated protein 1; Tras1; Tras2 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 117540, 22038, 5359 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 24GB1550 | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O15162, P58195, Q9JJ00 | |
| PLSCR1 | |
| A synthesized peptide derived from human Scramblase 1 (aa 20-55). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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