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  6. TIGIT Monoclonal Antibody (MBSA43), Functional Grade, eBioscience™, Invitrogen™
  7. 17131602

TIGIT Monoclonal Antibody (MBSA43), Functional Grade, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-9500-050

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Product Code. 17131602

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Description

Description

The MBSA43 MAb reacts with human T cell immunoreceptor with Ig and ITIM domains (TIGIT), which is also known as VSTM3 or WUCAM. This 26 kDa protein is a member of the poliovirus receptor (PVR) family. The expression of TIGIT has been reported on NK cells, regulatory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells, but it is not expressed on B cells or naive CD4+ T cells. TIGIT may be upregulated on naive CD4+ T cells upon activation. TIGIT can interact with certain members of the PVR and PVR-like families, including CD155, and also mediates the interaction of NK and T cells with antigen presenting cells, fibroblasts, and endothelial cells that express PVR and PVR-like proteins. MBSA43 is reported to crossreact with Rhesus macaque.

TIGIT Monoclonal antibody specifically detects TIGIT in Human samples. It is validated for Flow Cytometry, Functional Assay
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TIGIT
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
Q495A1
Mouse
50 mg
Primary
Human
Antibody
IgG1 κ
Flow Cytometry, Functional Assay
MBSA43
Functional Grade
TIGIT
ENSMUSG00000071552; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; tigit; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9; VSTM3; Washington University cell adhesion molecule; WUCAM
Affinity chromatography
RUO
201633
4° C
Liquid
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