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HPLC Columns and Cartridges

Pre-packed columns, cartridges, and guard columns for separation of biomolecules and organic/inorganic analytes; includes normal/reversed phase HPLC, UHPLC, LC-MS, HILIC, mixed-mode, ion exchange, ligand exchange, and affinity column formats.
HPLC Columns (52)
HPLC Guard Columns and Cartridges (1)

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1

Thermo Scientific™ Hypersil™ SAX HPLC Columns

Designed for aqueous and low pH mobile phases, Thermo Scientific™ Hypersil™ SAX LC Columns are highly stable silica-based quarternary amine strong anion exchange columns.

Pore Size 120 Å
Particle Size 5 μm
Stationary Phase Quaternary Amine
Temperature 60°C
Phase Ion Exchange
Endcapped Yes
Column Type Ion Exchange
Surface Area 170 m²/g
Max. Pressure 5800 psi (400 bar)
2

Thermo Scientific™ ProPac™ 3R SAX 3 μm HPLC Columns

Get the performance you need with ProPac™ 3R SAX HPLC columns. Suitable for charge variant separations and recommended for therapeutic proteins, mAbs, ADCs, and AAVs.

Pore Size Nonporous
Particle Size 3 μm
Stationary Phase Proprietary
Temperature Ambient to 60°C
Phase Strong Anion Exchange
Packing Material Monodisperse Polymer Resin
Column Type Ion Exchange
pH 2 to 12
Technique Bio-LC
Max. Pressure 4500 psi (310 bar)
Product Line ProPac
Column Format Analytical Column
3

Thermo Scientific™ Hypersil GOLD™ SAX HPLC Columns

Analyze smaller organic molecules, including nucleotides and organic acids, quickly and efficiently with Thermo Scientific™ Hypersil™ GOLD SAX LC Columns.

Pore Size 175 Å
Carbon Load 2.5%
Stationary Phase SAX
Temperature 60°C
Phase Ion Exchange
pH 2 to 8
Surface Area 220 m²/g
USP Type L14
4
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Thermo Scientific™ ProPac™ SAX-10 HPLC Columns

Use ProPac™ SAX-10 LC Columns for exceptionally high resolution and efficiency when separating protein variants.

Pore Size Nonporous
Particle Size 10 μm
Stationary Phase Quaternary Ammonium
Temperature 60°C
Phase Ion Exchange
Packing Material Spherical, Nonporous Polymer
Column Type Ion Exchange
pH 2 to 12
5

Thermo Scientific™ ProSwift™ SAX-1S HPLC Columns

For fast, high-resolution separation and purification of proteins by ion-exchange using the quaternary amine stationary phase, use Thermo Scientific™ ProSwift™ SAX-1S LC Columns.

Pore Size Monolith
Particle Size Monolith
Type Analytical Column
Stationary Phase Quaternary Amine
Temperature 70°C
Phase Ion Exchange
Length (Metric) 50 mm
Packing Material Monolith Polymer
Column Type Ion Exchange
pH 2 to 12
Product Line Monolith
Column Format Analytical Column
7

Hichrom™ HPLC column EXSAX-5-250A SAX ion exchange stainless steel 5μm 250mm x 4.6mm Exsil

ENCOMPASS
8

Hichrom™ SAX Quaternary Ammonium Ion Exchange HPLC Column, 5 μm, 4.6 mm x 150 mm

Column Format: Analytical Column; Carbon Load: 3%; Pore Size: 100 Å; Column Phase: Ion Exchange

ENCOMPASS
9

Thermo Scientific™ Acclaim™ Trinity P2 HPLC Columns

Use these mixed-mode columns for separation of multivalent cations or anions and pharmaceuticals.

Pore Size 300 Å
Solvents Compatible with most common HPLC organic solvents except for alcohols
Stationary Phase Spherical, Nanopolymer Hybrid Silica
Temperature 45°C
Phase HILIC and Ion Exchange
Endcapped Proprietary
Column Type Mixed Mode
Green Features FSC
Surface Area 100 m²/g
Max. Pressure 6000 psi (415 bar)
Particle Size 3 μm
Mobile Phase Compatibility 0 to 100% aqueous mobile phase
pH 2.5 to 7
Particle Shape Spherical silica
Product Line Acclaim
10

Thermo Scientific™ Hypersil™ SAX Columns, 5μm Particle Size

Highly stable silica-based quarternary amine strong anion exchange columns, designed for aqueous and low pH mobile phases

Pore Size 120 Å
Particle Size 5 μm
Carbon Load 2.5%
Phase Ion Exchange
Endcapped Yes
Column Type Ion Exchange
Diameter (Metric) 4 mm
Surface Area 170 m²/g
USP Type L14
Column Format Analytical Column