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CAS RN 284028-89-3

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CAS RN 284028-89-3

IUPAC Name: 2-[4-(trifluoromethyl)phenyl]-1H,4H,5H,7H,8H-thiopyrano[4,3-d]pyrimidin-4-one
Synonyms: 2-[4-(trifluoromethyl)phenyl]-1H,5H,7H,8H-thiopyrano[4,3-d]pyrimidin-4-one
Molecular Weight (g/mol): 312.31
Molecular Formula: C14H11F3N2OS
InChi Key: KLGQSVMIPOVQAX-UHFFFAOYSA-N
SMILES: FC(F)(F)C1=CC=C(C=C1)C1=NC(=O)C2=C(CCSC2)N1
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1 – 6 of 6 results
1

Tocris Bioscience™ XAV 939
GREENER_CHOICE

CAS: 284028-89-3 Molecular Formula: C14H11F3N2OS

CAS 284028-89-3
Molecular Formula C14H11F3N2OS
2

XAV 939, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

3

XAV 939, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

4

XAV 939, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

5

XAV-939, MedChemExpress

MedChemExpress XAV-939 is a potent tankyrase inhibitor that targets Wnt/β-catenin signaling. XAV-939 stabilizes axin by inhibiting tankyrase 1 and tankyrase 2 (IC50s of 5 and 2 nM, respectively), thereby stimulating β-catenin degradation. XAV939 binds tightly to the catalytic (PARP) domains of TNKS1 and TNKS2 (Kds of 99 and 93 nM, respectively).

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 312.31
Color Off-White
Physical Form Solid
Chemical Name or Material XAV-939
Grade Research
SMILES O=C1C(CSCC2)=C2N=C(C3=CC=C(C(F)(F)F)C=C3)N1
For Use With (Application) Cancer-programmed cell death
Percent Purity 95.0%
CAS 284028-89-3
Solubility Information DMSO : 25 mg/mL (80.05 mM; ultrasonic and warming and heat to 60°C) ∣H2O : < 0.1 mg/mL (insoluble)
Health Hazard 1 H301∣H319
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C14H11F3N2OS
Formula Weight 312.31
6

STEMCELL Technologies XAV939

WNT pathway inhibitor; Inhibits TNKS1 and TNKS2

ENCOMPASS_PREFERRED
CAS 284028-89-3
Purity ≥98%
Molecular Formula C14H11F3N2OS